Unformatted text preview: UNDER BASIC REACTION CONDITIONS is outlined below. Complete this mechanism by drawing curved arrows to show movement of electron pairs, and by drawing structures for each “missing” reaction intermediate. The final intermediate that forms is a resonance hybrid – please draw only the MOST IMPORTANT contributing resonance structure in the box provided. Ph C CH 3 O NH 2 NH 2 OH H OH OH + OH ∆ MORE IMPORTANT RESONANCE STRUCTURE Hydroxide departs as a leaving group - heating is required to overcome the activation barrier (a "strong" base is typically a "poor" leaving group) OH Ph C CH 3 N N H 2 H OH Ph C CH 3 O N NH 2 H H Ph C CH 3 O N NH 2 H Ph C CH 3 O N NH 2 H H Ph C CH 3 N H N H 2...
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- Spring '08
- Amide, ketone, Ph CH3 Ph, Ph Ph CH3