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Anatomy-MuscleDisorders,Review

Anatomy-MuscleDisorders,Review - Muscle Disorders Diseases...

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Muscle Disorders, Diseases, Review Human Anatomy and Physiology
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Muscular Dystrophy Group of inherited muscle- destroying diseases Different types Duchenne muscular dystrophy is most common 1 in 3,500 male births Gene on X chromosome, almost exclusively in men Mutated dystrophin gene
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Dystrophin Protein in sarcolemma Link thin filaments to sarcolemma Sarcolemma tears easily without dystrophin Muscle cell dies Stem cell treatments have been attempted Introduce myoblasts with gene for dystrophin Little success video
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Progression of DMD Noticeable symptoms at age 2-5 Difficulty with physical activities Unable to walk - around age 12 Death due to respiratory or cardiac failure - around age 20
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Hernias Protrusion of viscera through muscular wall of abdominopelvic cavity Inguinal hernia most common type of hernia (rare in women) viscera enter inguinal canal or even the scrotum Hiatal hernia
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  • Fall '07
  • TLGillian
  • Myasthenia gravis, Inguinal hernia, Muscular dystrophy, Duchenne Muscular Dystrophy, ACh receptors Receptors

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