Session 4 - Tissue Stem Cells Skin

Session 4 - Tissue Stem Cells Skin - Tissue Stem Cells kin...

Info iconThis preview shows pages 1–14. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Tissue Stem Cells kin Skin 1/31/07 Blastomere Totipotent SC l i t t Ectoderms ESC- Pluripotent Mouse ESC Endoderm esoderm Germ line Mesoderm Human ESC Ectoderms Endoderm Mesoderm Germ line Trophoblast Sea urchin gastrulation A cross section through the trunk of an amphibian embryo fter the end of gastrulation showing the arrangement of after the end of gastrulation, showing the arrangement of endodermal, mesodermal and ectodermal tissues. Putative ontogeny and classification of stem cells Putative ontogeny and classification of stem cells Gastrulation Gastrulation Nervous tissue Nervous tissue Neuronal stem cells Neuronal stem cells Ectoderm Ectoderm Blastocyst Blastocyst Skin Skin Skin stem cells Skin stem cells Mesoderm Mesoderm Embryonic Embryonic stem cells stem cells Bone marrow and blood Bone marrow and blood Mesenchymal/hematopoietic SCs Mesenchymal/hematopoietic SCs Muscle and bone Muscle and bone Tissue SCs Tissue SCs ung liver pancreas ung liver pancreas Endoderm Endoderm Lung, liver, pancreas Lung, liver, pancreas Organ specific SCs Organ specific SCs Esophagus, stomach, Esophagus, stomach, rimordial germ cells rimordial germ cells intestine/ intestine/ Intestinal SCs Intestinal SCs Adapted from “Handbook of Stem Cells” Adapted from “Handbook of Stem Cells” Primordial germ cells Primordial germ cells Formation of skin starts by interactions between mesoderm and ectoderm Organization of the skin and the hair follicle Epidermis Dermis Hair follicle Adapted from Alonso&Fuchs, 2003 Epithelial-Mesenchymal Interactions Govern Hair Follicle Morphogenesis In the same time the epidermis stratifies and matures Hair morphogenesis Rendl, M (2005) PLoS Biol 3(11): e331 Organization of the skin and the hair follicle Epidermis Basal layer Dermis Outer root sheath ner root Sebaceous gland Hair follicle Bulge stem cells Inner root sheath Hair shaft Dermal papillae Matrix Adapted from Alonso&Fuchs, 2003 The stratification of the epidermis Invasion by other cell types As epidermis stratifies and hair follicles form, the skin is invaded by blood vessels (endothelial cells), blood cells, and sensory nerves)...
View Full Document

This note was uploaded on 09/28/2008 for the course BIO 4400 taught by Professor Tumbar,td during the Spring '07 term at Cornell.

Page1 / 38

Session 4 - Tissue Stem Cells Skin - Tissue Stem Cells kin...

This preview shows document pages 1 - 14. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online