Stem Cells in Tissue Engineering

Stem Cells in Tissue Engineering - Stem Cells in Tissue...

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tem Cells in Tissue Engineering Stem Cells in Tissue Engineering 4/16/07
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Definition 1: Tissue engineering is the emerging discipline of design and construction of spare parts for the human body to restore function based on principles of molecular developmental biology in combination with supportive 3D matrices and biomolecules. Definition 2: Tissue engineering focuses on delivery or in situ mobilization of capable cells to restore pathologically altered architecture and function of tissues.
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What it takes to build a tissue • The three key ingredients for both orphogenesis and tissue engineering are: morphogenesis and tissue engineering are: – inductive signals, – responding stem cells, – the extra-cellular matrix.
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“The Growth of Tissue Engineering”, 2001
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Tissue engineering: “The end of the beginning”, 2004 By the close of 2002, twenty tissue-engineered products had entered Food and Drug Administration clinical trials. o r ere appro ed b t none of these are et commerciall Four were approved but none of these are yet commercially successful. Six other applications were either abandoned or failed to achieve product approval. Ten products were still in clinical trials, some of which were investigator sponsored, and most of which were at the phase I/phase II stage. The field has yet to produce a profitable product despite an ggregate research and development investment exceeding $4 5 aggregate research and development investment exceeding $4.5 billion.
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Stem Cells in Tissue Engineering - Stem Cells in Tissue...

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