Session 01 - Welcome to BioGD 440 Stem Cell Biology

Session 01 - Welcome to BioGD 440 Stem Cell Biology - Stem...

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Stem Cell Biology: Basic Science and Clinical Application Warren Hall Monday: RM 201 Wednesday: RM 345 & Rockefeller 132 structor: Tudorita Tumbar (DOINA) Instructor: Tudorita Tumbar (DOINA)
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“We are drawn to the subject of stem cells as we are to stories of perpetual motion machines or the fountain of youth; understanding the inner workings of stem cells might help to realize their mythic promise.” l S dli (2001) N t 414 98 Alan Spradling (2001), Nature 414:98
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What makes stem cell biology so exciting?
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Potential US Patient Population for Stem Cell- d T h i Based Therapies Condition Number of patients Cardiovascular disease Autoimmune disease i b t 58 million 30 million 6 illi Diabetes Osteoporosis ancer 16 million 10 million 2 million Cancer Alzheimer disease Parkinson disease 8.2 million 5.5 million 5.5 million Burns (severe) Spinal cord injuries 0.3 million 0.25 million Birth defects 0.15 million/year Stem Cells and the Future of Regenerative Medicine, 2004
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“I become uncomfortable whenever I hear i th t d ib th i b fit t b claims that describe the precise benefits to be derived from [stem cell] research- especially ht h i t d i t h t il i [ ] when they are associated with a timeline. […] Eventually, we will be able to use our profound no ledge of biolog to gro ne organs that knowledge of biology to grow new organs that can be safely transplanted into human patients ] B t the research [on stem cells] is eq all […]. But the research [on stem cells] is equally likely to contribute to cures for cancer and for a rge number of less famous diseases any of large number of less famous diseases - many of mysterious origin - that are terrible afflictions r humanity” for humanity” Bruce Alberts (2004), Handbook of Stem Cells
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Basic science promise • Unique abilities: em cells have the “power of choice”:self- stem cells have the power of choice : self renew and differentiate – many genes expressed by stem cells are of unknown function: “By studying stem cells will we discover new cellular functions?”
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Skin and hair follicle stem cells
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BioGD 440 Instructors • Professor: Tudorita Tumbar (Doina) •T A Ying Zhang [email protected] 5-6542 [email protected] 5-0518 Office hours: 3-5 PM Tuesday iotech 260 Office hours 2-4 PM Tuesday iotech 258 Biotech 260 Biotech 258
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lass resources Class resources Login into the backboard class web site http://blackboard.cornell.edu/ • Browse/College of Agriculture and Life Sciences/ Molecular Biology and Genetics/BioGD 440/Stem Cell Biology nroll for the class at the address below find how: Enroll for the class, at the address below find how: http://www.cit.cornell.edu/atc/cst/howto_selfenroll.sht ml • Download pdf files with your reading assignments (available the week before on Wednesday by Midday) • Power point lecture slides (Before Noon, Monday)
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Website organization • Course Information – Syllabus – Objectives – Overview ourse documents • Course documents – Session I - XXVIII – Readings – Research paper – Lecture slides (Final form in Monday by noon)
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Class organization • 28 sessions total/ XIV weeks
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This note was uploaded on 09/28/2008 for the course BIO 4400 taught by Professor Tumbar,td during the Spring '07 term at Cornell.

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Session 01 - Welcome to BioGD 440 Stem Cell Biology - Stem...

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