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week_2_cells_of_the_brain_1_3_slides

week_2_cells_of_the_brain_1_3_slides - Cells of the Brain...

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Temple, 2006 1 Cells of the Brain: Neurons & Glia Week 2, Lecture 1 Temple, 2006 2 Nervous System Nervous System Central Peripheral Brain Spinal Cord Somatic Autonomic Cranial nerves Spinal nerves Sympathetic Para- sympathetic Temple, 2006 3 Nervous System Nervous System Central Brain Spinal Cord Forebrain Brainstem Cortex Basal Ganglia Limbic System Diencephalon Midbrain Hindbrain
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Temple, 2006 4 Nervous System Nervous System Peripheral Somatic Autonomic Cranial nerves Spinal nerves Sympathetic Para- sympathetic Cervical Thoracic Lumbar Sacral Coccygeal Techniques Excellent time info OK spatial info Measure magnetic field produced by neurons from scalp MEG Excellent time info Measure electric field produced by neurons from scalp ERP Functional: Electrical Shows function Can label other chemicals Bad time and not so good space info Label blood flow in response to neurons’ activity with radioactive isotopes PET Shows function Good spatial info Bad time info Non invasive Detect magnetic properties of oxygen in blood flow response to neurons’ activity fMRI Functional: Metabolic Can give info about diseases Uses X-rays CT Excellent detail Non-invasive Measure magnetic properties of water MRI Structural Features Principle Instrument Technique Temple, 2006 6 Methods for Studying Human Brain Structural – MRI CT scan Functional Metabolism techniques • fMRI • PET Electric/magnetic techniques EEG / ERP • MEG – Stimulation Disease Models – Lesions – Disorders
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Temple, 2006 7 Stimulation Intra-operative brain stimulation TMS: Trans-cranial Magnetic Stimulation Temple, 2006 8 Diseases and Lesions Temple, 2006 9 Plan for today: Cells of the brain • Neurons – Parts of a neuron – Types of neurons • Glia – Types of glia – Focus on Clinical Disorders Multiple Sclerosis
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Temple, 2006 10 Neuron Structure Temple, 2006 11 Neuron Parts Temple, 2006 12 A Neuron
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