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lecture23 - BioEE 278 Evolutionary Biology Fall 2007...

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BioEE 278 Fall 2007 Evolutionary Biology Lecture 23 EVOLUTION AND DEVELOPMENT Chapter 20, focus on pp. 473-484. Boxes 20a and 20b provide background information. You are NOT responsible for the detail in these Boxes A. Origin of novelty 1. How do new structures and new functions arise? a. development mediates mapping of genotype to phenotype. b. definition c. temporal & spatial component 2. Change over time in morphology can be understood in terms of changes in development. a. change in genes determining morphology vs. changes in regulation of these genes. 3. The basic components of gene regulation. a. transcription factors and DNA binding sites b. trans -acting and cis -acting regulatory elements c. focus on transcription factors 4. Fundamental observations. a. many of the same genes determine patterns of development in animals b. these conserved genes are expressed at different times and different places during development 5. Homeotic genes a. control segment identity and body plans b. mutations in these genes tranform one body part into another or suppress development
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