Endocrine System 11-13 - Endocrine System Endocrine...

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Endocrine System
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Endocrine Connections Hormones are chemical messengers, that regulate all body functions Target tissue has specific receptors that bind the specific hormone. Endocrine Glands Secrets directly into the bloodstream Metabolism, Growth, Sleep, Mood Exocrine Glands Sends chemicals via ducts to the outside Salivary, Sweat, Mammary, Tears,
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Thyroid Gland Hormones: Thyroxine T4 & Tri-iodothyronine T3 Synthesized from iodine Needed for all cell metabolism, O2 uptake and metabolic rate Calcitonin: Secreted when Ca too high in blood, moves blood Ca to bone Calcitonin spray - a treatment for osteoporosis. _________________________________________________________________________________________________ Pathology: Hypersecretion Overactive = thyrotoxicosis Hyperthyroidism - Graves disease, autoimmune disease HR, temp, activity, Exophthalmia-eye protrusion Tx: radioactive iodine to obliterate thyroid tissue/anti thyroid drugs Hyposecretion Goiter = thyroid enlargement, low levels of T3, T4 due to low or no iodine also any condition causing damage to gland Hypothyroidism- fatigue, muscular and mental sluggishness, weight gain, fluid retention, low body temp, Low BP, constipation Myxedema – In adults, no output of hormones, atherosclerosis increases, dry skin & edema Hashimoto's thyroiditis- autoimmune disease, antibodies trigger destruction of thyroid Cretinism – In children, inhibited bone growth, redundant soft tissue, therefore looks obese, short, leads to poor physical & mental development Tx: Access to Iodine supplement and thyroid hormone replacement
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Thyroid Gland
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Parathyroid 4 small bodies on the dorsal surface of the thyroid Hormone:
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