501Exam08Fall-1

501Exam08Fall-1 - Biochemistry 501 Exam I September 29th,...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Biochemistry 501 Exam I September 29th, 2008 Indicate your answers to questions 1-33 by marking the correct answer on the answer sheet with a #2 pencil. All questions are worth 3 points for a total of 99. Enter your name and ID number on the answer sheet. Math Hints: 10 -2 = 0.01, 10 2 = 100, 10 -0.6 = 0.25, 10 0.6 = 4 1. Formation of a peptide bond is an example of what type of reaction? A) Hydrolysis B) Group transfer C) Rearrangement D) Condensation E) Oxidation 2. Pick the amino acid that does not have a chiral carbon center: A) Alanine B) Glycine C) Proline D) Histidine E) Arginine 3. Naphthalene binds specifically to the enzyme naphthalene 1,2-dioxygenase. What is the thermodynamic driving force that makes naphthalene binding to the enzyme a favorable event? Naphthalene A) Napthalene binding to the enzyme is stabilized by a favorable enthalpy due to hydrogen bonding and ionic interactions. B) The displacement of water from naphthalene and the enzyme results in an increase in entropy. C) The enzyme has a polar binding site that is complimentary to the substrate. D) all of the above E) A and B 4. Which of the following properties of water is false? A) The unpaired electrons on the oxygen give the atom a partial negative charge. B) Water is able to interact with both positively and negatively charged molecules. C) Water is dipolar and can form multiple hydrogen-bonds with other water molecules D) Water is a good solvent for non-polar compounds. E) Water has a high melting temperature and boiling point relative to other liquids.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 5. The pKa’s of arginine are 2.0 and 9.0 and 12.5. What is the isoelectric point of arginine? Choose the closest answer A) 9.0 B) 7.8 C) 5.5 D) 10.8 E) 12.5 6. In a 1 M solution of alanine at pH 7.7, what is the approximate percentage of amino molecules that will have amino groups in the NH2 form? The pKa’s of alanine are 2.34 and 9.70. A) 1 B) 10 C) 50 D) 90 E) 99 7. Lactic acid has a pKa of 4. At pH 3.4, what percentage of lactic acid is in the conjugate base form? A) 20 B) 25 C) 30 D) 35 E) 40
Background image of page 2
3 8. Which tripeptide is the most hydrophobic? A) Leucine-Glycine-Phenylalanine B) Lysine-Tryptophan-Alanine C) Isoleucine-Lysine-Glycine D) Glutamine-Aspartate-Arginine E) Histidine-Leucine-Glycine 9. What is the sequence of the following peptide? A) Glutamine-Alanine-Threonine-Aspartate B) Asparagine-Alanine-Threonine-Glycine-Aspartate C) Glutamine-Alanine-Threonine-Glycine-Aspartate D) Asparagine-Alanine-Threonine-Glycine-Glutamate E) Glutamate-Alanine-Serine-Glycine-Aspartate 10. Consider the following peptide: Gly-Ala- Lys-His-His- Gly-Glu-Gly Given that the approximate pKa's of Glycine are 2.3 and 9.5 Alanine are 2.3 and 9.7
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 09/30/2008 for the course BIOCHEM 501 taught by Professor Butcher during the Spring '08 term at Wisconsin.

Page1 / 8

501Exam08Fall-1 - Biochemistry 501 Exam I September 29th,...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online