wk7patho - Running head WK7 PATHO 1 wk7 patho April...

Running head: WK7 PATHO 1
wk7 patho
April Matthews
Walden University

WK7 PATHO 2
wk7 patho
Post an explanation of the pathophysiological mechanisms of iron deficiency anemia and the
anemia you selected. Compare these two types of anemia, as well as their potential causes.
Iron Deficiency Anemia
Iron deficiency anemia, it the most common type of anemia. In some developing
countries iron deficiency in the cause, in developed areas it is attributed to blood loss. Usually
the body stores enough iron to last several years. “Dietary iron is primarily absorbed by the
duodenum” (Hammer & McPhee, 2014 pg. 127). Iron is constantly in demand from the body,
and losing just 2-4 ml a day of blood containing 1-2 mg of iron can cause IDA. There are three
stages in which IDA develops. Stage 1 the body’s iron stores are depleted. The next stage not
enough iron is transported to the bone marrow causing iron deficient red cell production. The
third stage “begins when the hemoglobin-deficient red cells begin circulating to replace normal,
aged erythrocytes” (Hammer & McPhee, 2017 pg. 517). It is at stage three that clinical
manifestations are present.
Sideroblastic Anemia
Sideroblastic anemia is characterized by the ringed sideroblasts in the bone marrow.
These ringed sideroblast “are erythroblasts that contain iron-laden mitochondria arranged in a
circle around 1/3 or more of the nucleus” (Huether & McCance, 2017 pg.518). There are four
main types of sideroblastic anemias; acquired, reversible, congenital, and myelodysplastic. For