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Lecture+5+CHROMOSOME+STRUCTURE

Lecture+5+CHROMOSOME+STRUCTURE - Bio 97 Section D Midterm...

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Bio 97 Section D Midterm Review Wednesday, October 8 6-8 PM Room: ICS 174 Review packets at https://eee.uci.edu/programs/biotutor
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Free Bio 97 (Lec. A) Peer Tutoring Midterm 1 Review Where: PSCB 120 When: 6-8pm on Thursday, October 9 th , 2008 Please check the website below for Review Materials https://eee.uci.edu/programs/biotutor/ Email Dewey or Kevin for any special topic request(s)!
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Sample exam problem: Chloramphenicol is an antibiotic that inhibits the function of peptidyl transferase, a component of the 50S ribosomal subunit. This means that Chloramphenicol prevents the movement of the tRNA in the A site to the P site. Which of the following statements is TRUE ? a) Chloramphenicol will prevent the formation of the initiation complex b) Chloramphenicol will result in Alanine rather than Methionine being the first amino acid in all proteins c) Chloramphenicol will block elongation, but not translation initiation d) Chloramphenicol will cause the ribosome to work backwards and read the mRNA 3’ to 5’ as translation occurs bidirectionally in prokaryotes e) Chloramphenicol treatment produces the same effects as a “silent” mutation in the DNA
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Each human cell has 46 linear chromosomes and 6 billion base pairs of DNA . . . How do you fit all that DNA into a cell nucleus??! 5-1
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DNA in mammalian cells exists as chromatin Chromatin is a complex of DNA and proteins Chromatin is the material of which chromosomes are composed Chromatin in non-dividing cells is not condensed enough to see by light microscopy 5-2
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Chromosomes condense maximally during cell division http://www.nccr-oncology.ch/scripts/page9243.html 5-3
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