ppStimulants.pptx - Psychostimulants Chapter 6...

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Psychostimulants Chapter 6
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Psychostimulants Psychostimulants… sympathomimetic drugs Increase psychomotor and sympathetic NS activity Improve alertness and positive mood
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Psychostimulants – Ephedra The Chinese used a medicinal tea made from ma huang Active ingredients – pseudoephedrine and ephedrine Used to treat asthma OTC cold medication
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Psychostimulants – Amphetamines Class of drugs that share a similar structure 1887 Developed as mass producible form of ephedra World War II Used to improve alertness and reduce fatigue Adderall- treatment for ADHD and Narcolepsy
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Psychostimulants Methamphetamine 1919 Synthesized from ephedrine or pseudoephedrine Illicit manufacture is associated with toxic fumes Added methyl group Can be made relatively easily: Pseudophedrine, iodine, starting fluid, lye (Drano), paint thinner, and antifreeze
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Psychostimulants Methylphenidate ADHD treatment= Ritalin, Concerta Weak psychostimulant drug Recreational use often involved grinding up drug and snorting i Cathinone Leaves of Catha edulis ( khat ) Most potent psychostimulant Bath salts Synthetic cathinone
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Psychostimulants – Cocaine Coca- 5000 BC A bus that grows in the Andes Some people still chew coca leaves to reduce fatigue an increase productivity Medical use: Dr. W. S. Halsted used it as a local anesthetic Used in early versions of Coca-Cola and in many patent medicines
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Psychostimulants – Cocaine Freud studied use for treating Depression Morphine dependence
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