NST10 - Lect8 Metabolism - BMR - Energy expenditure when...

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1 BMR - Energy expenditure when sleeping RMR - Energy expediture when awake and rested after overnight fast What happens when total energy intake exceeds total energy expenditure (positive energy balance)? Metabolism How do we get energy from foods and body stores? How does the body coordinate its: a) use of carbohydrate, protein, and fat? b) synthesis (anabolism) and breakdown (catabolism) of body components? How do we get energy from foods and body stores? With oxygen = aerobic Energy Substrates (metabolic fuels): 1. Carbohydrates (dietary and glycogen glucose 2. Fat (triglycerides) fatty acids + glycerol 3. Protein amino acids
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2 Approximately 50 kg (110 lb) ATP used per day. Body contains about 10 gm (1/3 oz) ATP. Metabolic fuels are required to keep ATP/ADP ratio much higher than at chemical equilibrium. About 40 percent of the energy derived from metabolic fuels is ‘trapped’ as ATP, remainder released as heat. ATP can be used directly to drive reactions or indirectly via ion pumps. Can be used to produce additional energy sources - e.g. creatine phosphate in muscle Sodium-potassium ATPase pumps potassium into cells and sodium out of cells. The potassium and sodium gradients can drive reactions (e.g. active transport) ATP ADP + P Metabolic fuels come from the diet (macronutrients) and from body stores
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This note was uploaded on 10/12/2008 for the course NUTRI SCI 10 taught by Professor Amy during the Fall '08 term at University of California, Berkeley.

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NST10 - Lect8 Metabolism - BMR - Energy expenditure when...

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