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16-370_Final.docx - BIO/CHM 370 Final Exam May 5 2016 I...

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BIO/CHM 370 Final Exam May 5, 2016 I have taken this exam in compliance with the WFU honor code: __________________________________________________ Name __________________________________________________ Signature This exam consists of 17 questions and 7 pages for a total of 80 points. Make sure you pay attention to the point values for each question – don’t waste time on low-value questions and miss out on the higher value problems. 1. (5 pts) True or False. _____ Transition state analogs are often good drugs. _____ Acetylcholine readily passes through ion channels. _____ Fatty acids are carried in the bloodstream on serum albumin. _____ Glycogenin is a bypass enzyme used in gluconeogenesis. _____ Naturally occurring monosaccharides are predominantly D isomers. 2. (6 pts) Match the cofactors with their descriptions (list all that apply – you may use a description more than once, or for more than one cofactor): ____ TPP A. participates in hydride transfer reactions ____ FAD B. participates in decarboxylation reactions ____ NAD+ C. long flexible arm ____ Coenzyme A D. bound tightly to protein ____ Lipoic acid E. disulfide bond ____ Biotin F. reactive thiol 3. (6 pts) Match the Nobel Prize winners with their scientific discoveries: ____ Fred Sanger A. Crystal structure of hemoglobin
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