Physiology notes - immunology

Physiology notes - immunology - Physio 10.08 notes Shopping...

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Physio 10.08 notes Shopping for allele at each site to create IGs - Not enough: use enzymes to increase possibilities - Mu heavy chain is first of the molecules in any immune response that appears o IgM secreted by plasma cell - Then class switch: gamma replaces mu o IgG antibody of same specificity created - At end of response, no room for cells created, so apoptosis occurs o Memory B and memory T- lymphocytes remain o If immunization with attenuated live virus, immunity is lifelong Hep A Tetanus isn’t lifelong - B-cells specified, become plasma cells, then die - T-cells have broader opportunities o Thymus: Some T cells enter as pre-T cells Helper T cells are CD4-positive TH1 helper cells TH2 helper cells o Help B cells produce antibodies Cytotoxic T cells are CD8-positive T cells Not natural killer cells - T-cells o TCR and slg formed randomly—not in response to any antigenic stimulation o Early T-cells are both CD4 and CD8-positive o
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Physiology notes - immunology - Physio 10.08 notes Shopping...

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