Physiology notes - immunology

Physiology notes - immunology - Physio 10.06 notes In the...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Physio 10.06 notes In the lymph node, the action is between the B-cell and T-cell - Dendritic cell first interacts with T-cell using T-cell receptor - MHC II molecule interacts with bacterium, demonstrating it to the T-cell receptor o Genetically programmed to recognize only that epitope o Series of co-receptors next to T-cell receptor double-check over and over o CD4 molecule Present on all helper T-cells CD-3 is an aspect of the CD-4 receptor o CD28 o CD154 o MHC II holds the peptide fragment to which the T-cell receptor binds o CD40L aka CD154 Ultimately binds with the B-cell ligand CD40 Produces IL 4,5,6 o Maturation and proliferation of B-cells o Surface IG see different peptides, but cooperate to make single antibody with 1 specificity - Antibody molecules o Albumin peak of serum electrophoresis Largest Never found antibodies in here o Largest concentration found in gamma globulin Hence the name immunoglobulin - Multiple myeloma o Plasma cells that have gone back to the bone marrow
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 3

Physiology notes - immunology - Physio 10.06 notes In the...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online