Physiology notes- immunology

Physiology notes- immunology - Physio 9.29 notes Humoral...

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Humoral and cellular aspects of immunology Complement activation - PAMP activate complement Adaptive immune response 1 - Antigen and epitope-specific Adaptive immune response 2 - Humoral immunity Adaptive immune response 3 - Cell-mediated immunity o APC (antigen presenting cells), MHC + peptide o Grafts, e.g. – not natural phenomena Severe combined immune deficiency (SCID) - born without immune systems - can generate no immune response - “Bubble Boy” movie - No thymus at birth - Lymph nodes are tiny or nonexistent - Bone marrow is markedly abnormal AIDS - 1982 - about 60 million cases of HIV/AIDS o Half have died - 90% HIV infections exist in Sub-Saharan Africa - Learn about cells involved in immunity o CD4-positive helper T-cells missing in AIDS patients William Harvey discovered how the heart works Don’t it always seem to go/ that you don’t know what you’ve got til it’s gone Vaccination - William Jenner o Created vaccine for smallpox o Milkmaids Never got smallpox Found that people who survived smallpox had pockmarked
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Physiology notes- immunology - Physio 9.29 notes Humoral...

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