Lecture+5+Notes+C-D

Lecture+5+Notes+C-D - Lecture 5: Tour of the Cell IV...

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1 Lecture 5: Tour of the Cell IV Nucleus, ER, golgi, lysosome Monday 10/6/08 Bio 93, Fall 2008 Reading: Ch. 6, pgs 102-108 Dr. Marcelo Wood iClicker Question
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2 Relationship between organelles of the endomembrane Nucleus contains most of the genes in eukaryotic cells – Chromatin: DNA and associated proteins • Synthesis of mRNA – Nucleolus • Synthesis of rRNA • Formation of ribosomal subunits
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3 Nucleus is enclosed by double membrane Nuclear pores composed of nucleoporins Mediate transport in and out of nucleus iClicker Question
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4 • Ribosomes: synthesize proteins – Composed of rRNA combined with cytosolic proteins – 2 subunits, large and small – Free ribosomes • Synthesize cytosolic proteins – Bound ribosomes (to ER or nuclear envelope) • Synthesize integral membrane proteins and secreted proteins
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5 Endoplasmic reticulum – Continuous with nuclear envelope • Membranous tubules • Cisternae: internal space – Smooth ER • Ribosome free – Rough ER
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Lecture+5+Notes+C-D - Lecture 5: Tour of the Cell IV...

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