Lecture+4+Web-Bio93-2008

Lecture+4+Web-Bio93-2008 - Lecture 4: Cytoskeleton,...

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1 Lecture 4: Cytoskeleton, mitochondria, chloroplasts Friday 10-3-08 Bio 93, Fall 2008 Reading: Ch 6, Pgs. 109-118 Cytoskeleton in eukaryotic cells • A network of ±bers, extending throughout cytoplasm – Structural support – Motility • Structural elements of the cytoskeleton – Micro±laments (MF), microtubules (MT), intermediate ±laments (IF)
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2 • Cytoskeletal elements – Composed of subunits – Polarized (MT and MF) – Dynamic structures EM of cellular cytoskeleton after detergent extraction
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3 • Microflaments (actin): – Location – Structure – Assembly-disassembly – Function: • Cell shape • Transport o± cellular components over short distances • Cell motility (Crawling) • Muscle contraction: actin and myosin (motor protein)
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4 • Model of crawling movement mediated by MF Cytoskeleton in Prokaryotic cells? – Identi±cation of bacterial genes that are structurally related to actin
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5 Intermediate Filaments •Supercoiled into thick cables •Different subunits depending on cell type
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Lecture+4+Web-Bio93-2008 - Lecture 4: Cytoskeleton,...

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