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old midterm - PSYCHOLOGY 179 Do. 9901266" F. fave...

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Unformatted text preview: PSYCHOLOGY 179 Do. 9901266" F. fave Ml DTERM FALL 2005 JIqu lldillh. Last, FiI‘Sl :m ID number Version B WAIVER: By signing your name below, you waive your right to privacy. if you waive your right, your exam scores will be posted by identification number, outside the exam pick up room on the second floor of AP&M across the hall of the main eievator (no room number). This room will house the exams of those who sign the waiver. Tests, for those who sign the waiver, may be picked up from the Psychology Exam Pickup Room, on the second floor of AP&M, across the hall from the main elevators. If you choose NOT to waive your right to privacy, and do not Sign below, your scores will not be posted. Your scores and tests will be available only through Dr. Koob, or the TAs at their regularly scheduled office hours this quarter. I AGREE TO WAIVF. MY RIGHT TO man! AFV. lB 1. Which of the following psychedelic drugs is considered an "empathogen" because of its effects in producing enhanced feelings and affinity for others? a. psilocybin b. Inescaline @L)methylenedioxymethamphetamine—MDMA d. lysergic acid diethylamide 2. Which of the following drugs is more potent than morphine in producing pain relief? a. methadone (Dolophine) b. meperidine (Demerol) @fentanyl (Sublimazc) it]. all of above 3. A chipper in the context of opioid use follows a number of rules all of which are linked to which of the following? a. taking enough opioids all the time to avoid withdrawal Q?) maintaining control over opioid use under limited access conditions c. someone who uses in bi nges just to the point of becoming physically dependent and then stops d. a person that goes into detoxification so as to lower the cost of their opioid taking behavior 4. Which of the following is a criteria for Substance Dependence on a given drug as defined by the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM IV)? @there is a persistent desire or unsuccessful efforts to cut down or control substance use b. use of an illegal substance for intoxication c. there is a need for markedly decreased amounts of the substance to achieve intoxication (sensitization) d. all of above 5. The therapeutic index of a drug is which of the following? Kit) lethal dose 50% divided by the effective dose 50% b. effective dose 50% divided by the lethal dose 50% c. lethal dose 100% divided by the effective dose 50% d. . effective dose 100% divided by the lethal dose 50% 6. Effectiveness of a drug is defined as which of the following? a. dose required to produce an effect relative to a standard b. percent of a response relative to another drug 28 c. dose required to produce an effect relative to any other drug @percent of maximum response I Withdrawal from tobacco has which of the following characteristics"? 'Qfirritability, anxiety, sleep disturbances and increased hunger b. sleepiness. fatigue. decreased hungen increased blood pressure and heart rate c. hyperexcitability, tremor, increased blood pressure and heart rate and body temperature d. none of above, withdrawal from tobacco does not produce a withdrawal syndrome 8. Marijuana has which of the following effects on memory? @narijuana impairs the ability to consolidate new information and recall old information while intoxicated b. marijuana impairs only the ability to remember old information while intoxicated c. marijuana produces longterm memory impairments that outlive the acute intoxication 'd. marijuana has no negative effects on memory 9. What happens if an opiate addict maintained on methadone (Dolophine) is given a low to moderate dose of naloxone (Narcan) intramuscularly? (EL/nothing __b_._the high associated with methadone is blocked immediately .cL'the subject has a euphoric~like response _.Z)@he subject experiences an immediate and intense opiate withdrawal 10. Which of the following is considered a flashback preriencing psychedelic—like effects such as trails of moving objects, intensified co ors, flashes of light long after the acute intoxication has worn off b. psychedelic-like effects when taking a non psychedelic c. memory of things that one has done while intoxicated on a psychedelic drug months or years later (2!. failure to remember events that transpired while one was intoxicated with a psychedelic drug 11. Which of the following drugs or drug preparations is most likely to produce addiction (as defined by Dr. Koob) in those who have ever used the drug? 3. alcohol b. heroin c. cocaine @tobacco 313 12. Which of the following psychedelic drugs has pronounced analgesic effectst pronounced effects on body image. profound disorganized thinking but few visual perceptual changes? a. methylenedioxymethamphetamiae (MDMA) —-\,®hencyclidine (PCP} c. atropine d. dimclltyltryptaminc (DMT) l3. Cocaine or amphetamine abuse follows best which of the following patterns? a. euphoria->paranoia-3- (lysphoriao- psychosis b. paranoia->psychosis-> dyspltoria->euphoria c. paranoia->dysphoria—>euphoria->psychosis @euphoria->dysphoria~>paranoia—>psyehosis [4. When Dr. Albert Hoffman wrote in his journal: " My ego seemed suspended somewhere in space. from where I saw my dead body lying on the sofa" is best an example of which of the following? ' depersonalization 'b. synesthesia c. transcendental experience (1. recollective analytical experience 15. Tolerance caused by more rapid elimination of a drug is called which ofthe following? a. pharmacodynamic tolerance -b._context specific tolerance @drug disposition tolerance d, behavioral tolerance 16. A schedule 1 drug is a drug that meets which of the following criteria a. medical use and low abuse potential b. medical use and modest abuse potential c. medical use and high abuse potential @110 medical use and high abuse potential 17. Which of the following opioid drugs when synthesized elicitly has been shown to produce contaminants that cause Parkinson's Disease when it is intravenously Injected? ® meperidine (Demerol) b. heroin c. oxycodone (Oxycontin) 4B d. hydrocodOne (Vieodin) 18. Which of the following drugs or drug preparations is most likely to produce addiction (as defined by Dr. Koob) in those who have ever used the drug? , (NH . ‘._-._=_:.\ .i '~ -~ wfr' \‘ in full».- Eflcohol I ."“ . b. heroin c. cocaine d. tobacco 19. Doses of caffeine in excess of 500 mgtday increase (at least double) the incidence of which of the following? imityocardial infarction and coronary artery disease b. cancer of the gastrointestinal tract c. kidney disease d. all of above 20. "The guide asked me how I felt and I responded "Good" . As I uttered the word "Good" i could see it form visually in the air. it was pink and fluffly like a cloud" best describes which of the following psychedelic experiences? a. depersonalization @ynesthesia c. transcendental experience (J. autonornic effects 21. Which of the following routes of administration is most equivalent to an intravenous injection of a drug? ---a_. oral b. intramuscular c; intranasal @Iihaled " 22. Tolerance caused by more rapid elimination of a drug is 'alled which of the ‘ following? I/ -‘.‘I- \‘\\/;l ‘ ‘\{f ‘It I I r .I ‘I . - a. pharmacodynamtc tolerance - K b. context Specific tolerance I ‘.'\ .' ©li'ug disposition tolerance d; behavioral tolerance 23. The stage of a psychedelic experience where the boundary between self and environment may dissolve so completely that the drug user feels at one with other people. SB animals or the universe as a whole best describes which of the following stages of a psychedelic experience? a. symbolic stage b. recollective analytical stage @ntegral stage (I. perceptual stage 24. Tolerance to caffeine has which of the following characteristics? @olerance to the psychostimulant effects is rapid and dramatic within 3-5 days b. there is cross tolerance of caffeine to other stimulants such as amphetamines c. there is differential tolerance such that tolerance develops rapidly to the psychostimulant effects, but sensitization occurs to the autonomic effects d. all above 25. The history described in class of an army colonel who experienced chronic anxiety. restlessness, tremulousness. and digestive disturbances experienced the effects of chronic use of which substance? 3. methamphetamine CB caffeine c. cocaine d. alcohol I\- , _ . . l I " I 5' _ _. ‘ ---\ ,- 26-_ Which of the following 18 consrdered a flashback \{N‘H if Lia-C’s;- ' . " \v’ l‘ " ‘- “f! " .r— ' if inexperiencng psychedelic-like'e'ffects such as trails of moving objects, intensified colors, flashes of lightjonfiter the acute intoxication has worn off b. psycltedeliélilge’e’ffects when taking a non psychedelic ©nernoryof’flfing\s~th\at one has done while intoxicated on a psychedelic drug months or ears/later “ d;_,.fa'i|ure to remember event‘s'*tllat transpired while one was intoxicated with a _,/psychedelic drug ' 27. Which of the following drugs contains the active ingredient in marijuana and a legally available treatment for the nausea and vomiting of cancer chemotherapy and the loss of appetite of the AIDS wasting syndrome? a. rimonabant (Accomplia) b. buprenorphine (Subutex) c. buproprion (Zyban) @dronabinol (Marinol) 28. Dependence with a big "D" is which of the following, according to Dr. Knob? 6B a. acute withdrawal from a drug ofabuse b. tolerance and acute withdrawal front a drug of abuse c. drug abuse @hug addiction 29. Withdrawal from a long acting opioid drug compared to a short acting opioid drug is which of the following? a. withdrawal is shorter and more intense b. withdrawal is shorter but less intense c. withdrawal is longer but more intense @withdrawal is longer but less intense 30. Which of the following is a behavioral effect of a cannabinoid antagonist that currently is being proposed to the Food and Drug and Administration for therapeutic use. a. anti-aggression agent b. cognitive enhancement c. stimulant effects .ppetite suppression 31. Marijuana is classified as which of the following? a.sedafive b.hypnodc c.psychedehc @ll of above 32. Nicotine has which of the following paradoxical behavioral effects? a. increases hunger @lecreases anxiety c. increases pain (i. all of above 33. Goal directed but meaningless activity produced by cocaine or methamphetamine has been called which of the following? a. depersonalizatiori b. crank bugs @unding . paranoia 34. Running nose. teary eyes. yawninO. perspiration, pupillary dilation. hot and cold flashes, aching bones and a muscles and a general flu—like state best describes withdrawal from which of the following drugs? TB a. marijuana b. cocaine c.. nicotine ®heroin 35. Allen Ginsberg's experience where he saw the "cosmic diamond cat” was best an example of which of the following? -a. 'recoliective-anaiytical stage of a psychedelic "trip" metaphyscial bad trip resulting from intoxication with a psychedelic c; cocaine psychosis cl. synesthesia resulting from intoxication with a psychedelic 36. What happens to feelings of mood and pleasure during the descending limb of the inverted u shaped function that describes the blood levels of cocaine over time after smoking coca paste? a. the euphoria decreases and follows (parallels) the decreases in levels of cocaine in the blood b. the euphoria comes on only after the decreases in levels of eccaine in the blood from the peak levels which produce catatonia -@the euphoria decreases much faster than the decreases in levels of cocaine in the blood and a dysphoria occurs even while cocaine is at high levels in the blood d. the euphoria remains high even after blood levels decrease back to zero. 3?. Which of the following drugs has been linked to Serotonin depictions in the brain with high dose administration in animal studies? a. marijuana b. LSD @nethyldioxyrnethamphetamine- MDMA . all of above 38. In opiate addiction "being straight” refers to which of the following? a. the rush associated with an injection straight into the vein b. the period after the acute severe withdrawal where everything is gray and not very pleasant ' @eriod after an injection of heroin after the high but before withdrawal sets in d. catatonia (muscular rigidity) associated with high dose intoxication 39. Which of the following part of the marijuana plant is most psychoactive? a. seeds @flowers SB C. Stem d. leaves 40. Increasing the dose of nicotine in a cigarette has which of the following initial effects? a. increaSes the number of puffs taken when smoking but decreases the number of cigarettes [3. decreases number of puffs taken when smoking but increases the number of cigarettes c. increases the number of puffs taken andfor the number cigarettes smoked @decreases the number of puffs taken andfor the number of cigarettes smoked '. 3 ' r. ' ‘la \ 41. extra point question ii, _"- ,:;‘ .i .' ' .- cc .5.» t Which of the following would the basis for adding naloxone to buprenorphine (S uboxone) for the treatment of opiate dependence? :1. naloxone potentiates the effects of buprenorphine b. naloxone blocks the breakdown of buprenorphine allowing more buprenorphine to be available to the brain ®aloxone is not active given orally but only active when given intravenously and thus it prevents the intravenous use of buprenorphine but does not prevent the prescribed oral use of burprenorphine d. naloxone blocks only the euphoric receptors for opioids leaving buprenorphine to continue to block pain 98 ...
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old midterm - PSYCHOLOGY 179 Do. 9901266" F. fave...

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