Topic 9 Slides - The cell cycle Semiconservative...

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The cell cycle Phases are G1, S, G2, M During division, the cell moves through each phase in order Time spent in each phase varies according to the cell type Nondividing cells are in G1 or G0 Semiconservative Replication Strands separate DNA polymerase attaches nucleotides in new strand based on complementary base pairing Strands made in both direction using both strands as templates Phases of Mitosis (M) Checkpoint control of the cell cycle
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Evidence that proteins regulate cell cycle progression Characterization of MPF Activity Maturation Promoting Factor (MPF) is isolated from different organisms Regulation of MPF activity and cyclin levels during the cell cycle Regulation of cell cycle by Cdk-cyclin complexes
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Destruction of M cyclin Inhibition of a Cdk-cyclin complex Checkpoint control of the cell cycle Cyclin/Cdk Complexes
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G1-Cdk triggers passage from G1 to S DNA has a re-replication block S-Cdk regulates DNA replication M-Cdk (MPF)controls passage from G2 to M
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This note was uploaded on 10/23/2008 for the course BIOL 201 taught by Professor Prichard during the Winter '08 term at University of Alberta.

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Topic 9 Slides - The cell cycle Semiconservative...

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