Exam_3_Key - Biochemistry 461 Midterm III-2006 Name...

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1 Biochemistry 461 Midterm III-2006 Name __________________ Student Number Signature __________________ This exam consists of 7 pages ---- Be sure you have all 7 pages. Total Points = 100. The answers to the questions must be placed on the bubble sheet. Questions 1-10 (1 point each) Choose the word, from a) to j), that fits best in the statement below. You can use each word only once. a. FBPaseII/PFKII b. Fructose 6 phosphate c. glucagon d. adenylate cyclase e. protein kinase A f. G-protein g. glucose h. GTP i. Fructose 2,6 bisphosphate j. GDP You are stranded in a desert island and have not eaten for two days. Under such conditions you will have increased concentration in blood of a hormone called 1 . This hormone will travel to cells and bind to receptors associated with a 2 complex . Upon stimulation, the occupied receptor will change shape and interact with the complex, leading to the release of 3 and binding of 4 . The α subunit then dissociates from the complex and activates the enzyme 5 . Upon activation, this enzyme will convert ATP to cAMP. Increased levels of cAMP will activate the enzyme 6 which in turn will phosphorylate 7 and result in the conversion of 8 to 9 . The resulting changes are important for the synthesis of 10 . Questions 11-40 (3 points each) 11. The main function of the pentose phosphate pathway is to: A. give the cell an alternative pathway should glycolysis fail. B. provide a mechanism for the utilization of the carbon skeletons of excess amino acids. C. supply energy. D. supply NADH. E. supply pentoses and NADPH.
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2 12. Glucose breakdown in certain mammalian and bacterial cells can occur by mechanisms other than classic glycolysis. In most of these, glucose 6-phosphate is oxidized to 6- phosphogluconate, which is then further metabolized by: A. an aldolase-type split to form glyceric acid and glyceraldehyde 3-phosphate. B. an aldolase-type split to form glycolic acid and erythrose 4-phosphate. C. conversion to 1,6-bisphosphogluconate. D. decarboxylation to produce a ketopentose. E. oxidation to a six-carbon dicarboxylic acid. 13. The oxidation of 3 mol of glucose by the pentose phosphate pathway may result in the production of: A. 2 mol of pentose, 4 mol of NADPH, and 8 mol of CO 2 . B. 3 mol of pentose, 4 mol of NADPH, and 3 mol of CO 2 . C. 3 mol of pentose, 6 mol of NADPH, and 3 mol of CO 2 . D.
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This note was uploaded on 03/19/2008 for the course BMB 461 taught by Professor Stoltzfus during the Fall '07 term at Michigan State University.

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Exam_3_Key - Biochemistry 461 Midterm III-2006 Name...

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