Bio 182 (7).pdf - BIO 182 General Biology II Spring...

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1 BIO 182: General Biology II Spring Semester 2011 Chapter 13 Mendel and the Gene Cayle Lisenbee UCENT 355 (602) 496-0641 [email protected] Office Hours: Mon/Wed 3:00-5:00 pm, Tue/Thu 12:00-1:00 pm Instructional Aides: Neda Javidan, Alex Gannon, Kristina Flynn Complex Inheritance and Pedigrees Pleiotropy A gene that influences many traits rather than just one trait is said to exhibit pleiotropy . The gene responsible for Marfan syndrome , a dominant trait in humans, is a good example of pleiotropy. Research suggests that the syndrome is caused by a mutation in the FBN1 gene that codes for fibrillin-1, a glycoprotein that is a primary component of elastic fibers in connective tissue. Individuals exhibit a wide array of phenotypic effects, including tall stature, long limbs and fingers, lung and eye problems, and potential severe defects in the heart valves and aorta. 2/6/2011 2 BIO 182: General Biology II (Lisenbee) Olympic swimmer Michael Phelps has been diagnosed with mild Marfan’s syndrome.
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