patho test 1.docx - most common cause of cell injury...

Info icon This preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
most common cause of cell injury HYPOXIA (inadequate oxygenation), usually secondary to ISCHEMIA Explain the relationship between injury and disease All DISEASE is caused by INJURY Other causes of cell injury: a. Direct physical action: mechanical force, acids or alkalis that alter pH, heat or low temperature b. Ionizing radiation c. Toxic molecular injury d. Microbes e. Inflammatory and immune reactions f. Nutritional imbalance g. Genetic defects h. Aging Causes of cell atrophy a. Reduced functional demand b. Inadequate blood supply c. Lack of hormonal or neural support d. Chronic injury e. Cell aging dysplasia a premalignant change of cells typically seen in epithelium, in which the orderly arrangement or normal cells is replaced by a disorderly overgrowth of cells with enlarged, dark, irregular nuclei metaplasia the change of one cell type into another following stress of chronic mild injury; for example, the change of endocervical glandular epithelium into squamous epithelium as a result of chronic inflammation of the cervix (cervicitis) Necrosis the consequence of severe, irreversible cell injury the most common cause of necrosis and the most common type of necrosis Coagulative necrosis is most often caused by ischemia (inadequate blood flow) parenchymal cells Cells that provide the actual function of the tissue (as distinguished from supporting or connective tissues) Healing type of repair that occurs when regeneration is partial or not possible; some scarring is always present. stable cells may regenerate through stem cells, and which divide very slowly until stimulated by injury, after which they divide rapidly sequence the component steps in fibrous repair (scarring)
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Fibrocyte migration, angioneogenesis, and scar development granulation tissue a mixture of new blood vessels, fibrous tissue, and residual edema and leukocytes that is at its
Image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern