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NURS 6521N-36 – Advanced PharmacologyDiscussion Post Week 3 – Pharmacotherapy for Cardiovascular DisordersCynthia NwokochaJune 12, 2017Pharmacotherapy for Cardiovascular DisordersCardiovascular disease (CVD) is the leading cause of death in the United States. CVD is a group of disorders of the heart and blood vessels, and they include coronary heart disease, cerebrovascular disease, peripheral arterial disease; and rheumatic heart disease, congenital heart disease, deep vein thrombosis, and pulmonary embolism (Hajar, 2016). This week’s post will examine the pharmacotherapy for cardiovascular disorders.Case Study #3 Patient CB has a history of strokes. The patient has been diagnosed with type 2 diabetes, hypertension, and hyperlipidemia. Drugs currently prescribedinclude the following:Glipizide 10 mg po dailyHCTZ 25 mg dailyAtenolol 25 mg po dailyHydralazine 25 mg qidSimvastatin 80 mg daily
Verapamil 180 mg CD dailyRisk Factors and Associated Health IssuesHeart attacks and strokes are usually acute events and are mainly caused by arteriosclerosis involving heart or brain. The cause of heart attacks and strokes is usually the presence of a combination of risk factors, such as age, gender, ethnicity, tobacco use, birth weight, unhealthy diet and obesity, physical inactivity, alcohol abuse, hypertension, diabetes, and hyperlipidemia. CVD becomes more common with age, and are in fact diseases of aging. Around 83 million Americans are estimated to have one or more types of CVD, and 42 million of them are age 60 or older (Alliance for Ageing Research, 2017). At age 80 and older, 83% of women and 87% of men have some type ofCVD (Alliance for Aging Research, 2017). Age is a continuous risk factor for theoccurrence of stroke, with an increase in the incidence and prevalence rates for each successive 5 years after age 65 years (Arboix, 2015). Men show a higher incidence of stroke than women. Regarding ethnicity/race, it has been demonstrated that black patients have a higher incidence of stroke vs white patients (Arboix, 2015). Intracranial atherosclerotic disease is more frequent