BONES - BONES Feels like a rock, but its alive, living...

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BONES Feels like a rock, but it’s alive, living tissue Processes Growth Begins as cartilage as an infant. Active growth in long bones Continues until full length is achieved Then the growth centers close the epiphyseal plates Active growth is limited Remodeling o Continues through life Osteoblasts: builders of bone Job is to lay down protein matrix for form And put mineral in matrix for strength Osteoclasts: Opposes Osteoblasts Dissolve bone and the matrix Release the mineral into the blood. This happens to allow The bone to RESHAPE itself. o Then it can adapt to stress. The bone to heal injuries/breaks o Reform and reknit none The bone to be a calcium reservoir o Because oseoclasts can break bone down, we can store calcium in the bone and get it back when we need it. Blood calcium is tightly regulated Allows bones to adapt. Calcium is lucky it can be stored in bone because it is essential for: Muscle contraction Blood clotting Signal transduction Enzymes Blood calcium is maintained + 3% This is possible because of bone
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BONES - BONES Feels like a rock, but its alive, living...

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