WK10AssgnDavisNppx.pptx - SEPSIS Nina S Davis NURS 6501 Advanced Pathophysiology August 6 2017 WHAT D0ES SEPSIS MEAN Sepsis refers to an inflammatory

WK10AssgnDavisNppx.pptx - SEPSIS Nina S Davis NURS 6501...

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SEPSISNina S DavisNURS 6501: Advanced Pathophysiology August 6, 2017
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WHAT D0ES SEPSIS MEAN?Sepsis refers to an inflammatory response resulting of an infection. In severe cases , closely associated with acute and life threatening dysfunction of the organs It is closely associated with acute and life threatening dysfunction of the organs. 146,000–159,000 people diagnosed with sepsis annually.Major cause of illnesses in the emergency units, high dependency units and also the hospitals in general28 to 50 percent morality with patients diagnosis with Sepsis
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PATHOPHYSIOLOGYEndotoxins are introduced to the hostthis triggers the release of cd4 cells which in turn can causeAnti-inflammatory cytokinesTumor necrosis factorInterleukinsPlatelet aggregating factorAs a result activation of Hypothalamus: fever, tachycardia, tachypneaCapillary endothelial cell: neutrophil margination, platelet adherence, dic, depletion of intravascular blood volume
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