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Free energy and biochemical reactions Reading assignments: Molecular Biology of the Gene (Watson, 6th ed) chapter 3 p45-46, chapter 4 Outline concept of free energy chemical reactions involve changes in free energy ATP is the main source of energy in cells
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A + B AB Most chemical reactions are bidirectional At equilibrium, the forward and reverse reactions occur at equal rates. equilibrium constant K eq = [AB]/[A] [B]
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Making and breaking chemical bonds involves changes in the form of energy free energy (G) is the amount of energy available to do “work” (e.g.: thermal energy). Energy can interconvert between forms such as
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