Neurotransmitters, Synthesis, and Reuptake 9-17-08

Neurotransmitters, Synthesis, and Reuptake 9-17-08 - Three...

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What is a neurotransmitter? What is a neurotransmitter? Three criteria must be met for a substance to be a neurotransmitter. 1. It must be present within the presynaptic neuron. Also the enzymes and precursors that facilitate synthesis must also be present. However, some are needed for protein synthesis. 1. It must be released by depolarization of the presynaptic terminal. Must also require Ca 2+ influx. 1. Specific receptors must be present on the postsynaptic cell. Exogenous transmitters can mimic. Agonists and antagonists can alter transmission.
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Categories of neurotransmitters Categories of neurotransmitters
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Categories of neurotransmitters Categories of neurotransmitters
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The general architecture of ligand-gated receptors The general architecture of ligand-gated receptors Glutamate Receptors
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The general architecture of ligand-gated receptors The general architecture of ligand-gated receptors
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The structure of the nACh receptor/channel The structure of the nACh receptor/channel
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Acetylcholine metabolism in cholinergic nerve  Acetylcholine metabolism in cholinergic nerve  terminals terminals
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Transporters Transporters Move ions or small molecules against their gradients. Require energy to move.
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Neurotransmitters, Synthesis, and Reuptake 9-17-08 - Three...

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