Blood Class Notes.pptx - The Circulatory System Blood Functions and properties of blood Plasma Blood cell production Erythrocytes Leukocytes Hemostasis

Blood Class Notes.pptx - The Circulatory System Blood...

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The Circulatory System: Blood Functions and properties of blood Plasma Blood cell production Erythrocytes Leukocytes Hemostasis Blood types
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Functions of Blood Transports : _____ from lungs to organs/cells _____ from cells to lungs _________ from digestive system & storage Wastes to liver & kidneys ____________ Regulates body _______________ (transports heat out to skin) Immunity (white blood cells) Clotting (platelets) Stabilizes water balance Stabilizes _____ buffer for acids & bases
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Blood Adults have _______ of blood Blood is a connective tissue more matrix vs cells Blood Components _______ , a clear extracellular fluid (55% of blood) ___________________ - blood cells and platelets mean erythrocyte (RBCs) count – 4.2-6.2 million/ l mean leukocyte (WBCs) count – 5,000-10,000/ l mean platelet count – 130,000-400,000/ l
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Formed Elements of Blood Erythrocytes – red blood cells Leukocytes – white blood cells Granulocytes – have cytoplasmic granules Neutrophils Eosinophils Basophils Agranulocytes – no cytoplasmic granules Lymphocytes (T-cells & B-cells) Monocytes & Macrophages Platelets
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Formed Elements of Blood Neutrophil Erythrocyte Eosinophil Monocyte Neutrophil Basophil Neutrophil Platelets Monocyte Small lymphocyte Young (band) neutrophil Small lymphocyte Large lymphocyte
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Hematocrit Centrifuging blood forces formed elements to separate from plasma ______________ is % of total volume that is _______ Erythrocytes are heaviest and settle first 37% to 52% total volume White blood cells & platelets 1% total volume _________ coat Plasma 47% to 63% Centrifuge Withdraw blood Plasma (55% of whole blood) Buffy coat: leukocytes and platelets (<1% of whole blood) Erythrocytes (45% of whole blood) Formed elements
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Properties of Blood __________ - resistance to flow (thickness/stickyness) Blood is 4.5-5.5 times more viscous than water Plasma alone is 2 times more viscous than water Too many or too few red blood cells changes the viscosity of blood and puts a strain on the heart _____________ - total molar concentration of dissolved particles in 1 L of solution due to transfer of nutrients and wastes between the blood & tissue fluids If too high : bloodstream absorbs too much fluid from the tissues, thus causing hypertension (high BP) If too low : bloodstream transfers too much fluid to tissues, resulting in edema and hypotension (low BP)
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Plasma and Plasma Proteins 92% __________ Also contains proteins , enzymes , nutrients , wastes , hormones , lipids , trace elements, gases Serum - plasma minus the clotting proteins Proteins are the most abundant solute in plasma Used for clotting, defense and transport 3 categories of plasma proteins _____________ are most abundant plasma protein Produced by the liver contribute to viscosity and osmolarity and influences blood pressure, flow and fluid balance Fibrinogen - clotting Globulins ( _____________ ) - immune system defenses
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Blood Cell Production (Hemopoiesis) Hemopoietic tissues produce formed elements ________________ - produces RBCs, WBCs & platelets committed cells are destined to continue down a specific cell line Hemopoietic stem cells multiply continually & are pluripotent (capable of differentiating into multiple cell lines)
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