Founder Mutations

Founder Mutations - their children for having some kind of...

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Founder Mutations Dennis Drayna Founder mutations are a special kind of genetic mutation. The stretch of DNA containing the founder mutation is identical in all people who have the mutation. Founder mutations are extremely useful in research for several reasons. Founder mutations give information about the migrations of specific groups of people throughout history. Scientists can find this out by observing the length of the stretch of DNA containing the founder mutation and finding the person currently carrying the mutation. This can tell the scientists when the mutation first occurred. Since founder mutations can also pertain to certain ethnic groups, physicians can recommend testing to certain races or ethnic groups for specific diseases. There are advantages and disadvantages to knowing a person’s full genetic profile. One advantage is that if two people want to have children, they can find out what the risks are for
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Unformatted text preview: their children for having some kind of disease. This could also be a disadvantage because in some cases it might discourage the couple from having children. Another advantage is being able to trace the persons origins. Knowing someones genetic profile can give clues to who his or her ancestors were, which can be good for both the person and researchers. Another advantage is finding out which diseases the person is at risk for. To share a haplotype with someone is to share an ancestor. A haplotype is the stretch of DNA containing the founder mutation. The haplotype is identical in people who have the same founder mutation. The haplotype gets smaller in each generation. So to tell the age of the founder mutation, scientists look at the length of the haplotype in the person currently carrying the founder mutation. The longer the length of the haplotype, the younger the founder mutation....
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Founder Mutations - their children for having some kind of...

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