LECTURE 5:LECTURE 5:DNA, RNA & PROTEINSDNA, RNA & PROTEINSThe molecules of life
Today…•DNA structure and replication•RNA–Transcription–Translation•Protein synthesis–Amino acids
DNADNA•Deoxyribonucleic Acid(DNA) •is the blueprint for life: •contains __________________________
DNA structure•DNA is a polymer of nucleotidesEach nucleotide composed of ___________________________________________________
Four DNA bases•Four kinds of nitrogenous bases:•Purine bases•Pyrimidine bases
DNA: Complimentary base pairing•Adenine pairs with ________A •Cytosine pairs with _________C
DNA STRUCTURE•DNA is a ________ helix •Discovered by Watson and Crick, 1953
DNA REPLICATION (in the nucleus)•Each DNA strand becomes a _____________, parent strand becomes apart•Proper base-pairs areassembled on that template
DNA replication•Nucleotides are connected together to make a new strand that is ____________ to the old strand.•The new double strand is _________ to the old double strand•This is called ________________________replication
A-T vs.G-C bond•A-T is a doublebond…•C-G is a ______ bond (stronger)…•DNA double strand can separate into 2 single strands when heated.•Which strand would require more heat (more energy) to separate: an A-T rich or a C-G rich double strand?
RNA structure and synthesis•RNA: ___________________•Is very similar to DNA (repeating subunits, nucleotides).•Difference between RNA and DNA:Each nucleotide contains a different sugar: ____________instead of deoxyribose.Bases are A, G, C, and U (_________________) A pairs with ______; G pairs with ______
RNA•RNA is _________ stranded and shorter•RNA is less stable than DNA: RNA doesn’t persist in the cell for long (sometimes it exists for a few seconds),whereas DNA can persist for the life of thecell.
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