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Immunology - Lymphatic System Innate Immunity A...

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A. Introduction B. Lymphatic System C. Overview of Innate Immunity D. Barrier Defenses E. Cellular Defenses F. Chemical Defenses G. Inflammation 0 Lymphatic System & Innate Immunity
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General Functions of Immunity When it works … Defend against infection by viruses, bacteria, fungi, parasites Destroy and recycle worn-out cells Identify and destroy cancer cells When it doesn’t work … Allergies Autoimmune diseases Immunodeficiency diseases Limits tissue/organ transplants Types of Immunity Innate (non-specific) Acquired (specific)
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Lymphatic System Red bone marrow 0 Thymus Lymphatic ducts 0
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Innate Immunity – Overview Inherited Rapidly acting Requires no activation No memory of prior exposure Includes barriers, cellular, and chemical defenses Responds to a broad range of threats (non-specific)
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Innate Barrier Defenses Stratum corneum Sweat gland Oil gland Skin Ciliated Mucous Epithelium Skin A stratified squamous epithelium Stratum corneum is impervious Oil and sweat glands, pH 3-5 Mucus Sticky to trap foreign matter May be moved by cilia Normal Flora Competes with pathogens
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