Biochem415 Exam2 Key - Biochemistry 415/515 2008 October...

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Biochemistry 415/515 2008 Name ________________________ October 28, 2008 uniqname________________________ Biochemistry 415/515 Exam 2 of 4 100 points total Instructions: 1. Please put your name on each page of the exam, your uniqname on the first page and fill out the scantron sheet with your student ID number and name. 2. Read through the exam first. Answer the immediately obvious questions when you can. Put a question mark by the ones you’re not sure about. You may take up to 2 hours to complete the exam. 3. Note that we will be answering questions of clarification only. In fairness to the other students we will not be able to answer any questions involving content. 4. Make sure that you have answered all of your questions on the scantron sheet, including the true/false (True=A, False=B). Please turn in both your scantron sheets and your question sheets when you are done. Good luck! Section A. Multiple choice (33-2 points per question). Choose the single most appropriate answer. 1. Gluconeogenesis: a. Is the synthesis of glucose from noncarbohydrate precursors b. Maintains blood glucose levels during times of fasting and starvation c. Is simply glycolysis in reverse d. A and B e. A, B and C 2. The primary raw materials for gluconeogenesis are: a. galactose and sucrose b. glycerol c. lactate and alanine d. B and C e. A, B and C 3. Identify the gluconeogenic steps that bypass irreversible steps of glycolysis: a. pyruvate conversion to phosphoenolpyruvate via oxaloacetate b. fructose 1,6-bisphosphate hydrolysis c. hydrolysis of glucose-6-phosphate d. isomerization of glucose-6-phosphate and fructose-6-phosphate e. A, B and C Midterm Examination #2 Page 1
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Biochemistry 415/515 2008 Name ________________________ October 28, 2008 uniqname________________________ 4. Pyruvate carboxylase: a. Catalyzes a key regulatory step in glycolysis b. catalyzes the carboxylation of pyruvate to form oxaloacetate c. is activated by acetyl CoA d. B and C e. A, B and C 5. Which of the following enzymes utilize biotin as a cofactor: a. pyruvate carboxylase b. glycogen phosphorylase c. acetyl coA carboxylase d. A and C 6. Gluconeogenesis and glycolysis are reciprocally regulated. Which of the following favor/promote gluconeogenesis? a. ATP b. citrate c. fructose 2, 6 bisphosphate d. A and B e. A, B and C 7. The Cori cycle: a. links glycolysis in muscle to gluconeogenesis in liver b. links glycogen synthesis in muscle to glycolysis in liver c. connects fatty acid degradation in adipose tissue to fatty acid synthesis in muscle d. shuttles oxaloacetate through malate to connect cytosolic and mitochondrial reactions during gluconeogenesis 8. What is the role of pyridoxal phosphate in the reaction catalyzed by glycogen phosphorylase? a.
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This note was uploaded on 12/09/2008 for the course BIOLCHEM 415 taught by Professor Michaeluhler during the Fall '06 term at University of Michigan.

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Biochem415 Exam2 Key - Biochemistry 415/515 2008 October...

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