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Unformatted text preview: D O N O T R E D I S T R I B U T E Biochemistry 415/515 2008 Name _KEY ___________________ September 30, 2008 uniqname________________________ Midterm Examination #1 Page 1 Biochemistry 415/515 Exam 1 of 4 100 points total Instructions: 1. Please put your name on each page of the exam, your uniqname on the first page and fill out the scantron sheet with your student ID number and name. 2. Read through the exam first. Answer the immediately obvious questions when you can. Put a question mark by the ones youre not sure about. You may take up to 2 hours to complete the exam. 3. Note that we will be answering questions of clarification only. In fairness to the other students we will not be able to answer any questions involving content. Often you may be focusing on a phrase that can be stated differently and thinking about it for a moment will clarify things. If you feel you still absolutely must ask a question, raise your hand. 4. Make sure that you have answered all of your questions on the scantron sheet, including the true/false (True=A, False=B). Please turn in both your scantron sheets and your question sheets when you are done. Good luck! Section A. Multiple choice (76 points-2 points per question). Choose the single most appropriate answer. 1. In general terms, which of the following is true of all DNA double helices: (a) The chemistry of the two DNA strands are aligned in an anti-parallel orientation relative to one another with regard to the 5 3 directionality of the DNA backbone (b) The nucleic acid bases form favorable stacking interactions with one another due to van der Waals interactions between the atoms (c) An AT basepair forms more inter-strand H-bonds than a GC basepair (d) a and b above (e) a and c above 2. The disruption of what types of bonds largely explains why the DNA double helix is denatured at high pH: (a) covalent bonds (b) ionic bonds (c) hydrogen bonds (d) electrostatic bonds (e) a and c above 3. Which of the following types associations between two atoms will require the largest amount of energy to break? (a) Hydrogen (b) Ionic (c) Covalent D O N O T R E D I S T R I B U T E Biochemistry 415/515 2008 Name _KEY ___________________ September 30, 2008 uniqname________________________ Midterm Examination #1 Page 2 (d) Van der Waals 4. The dielectric constant of ethanol is less than the dielectric constant of water. This means that: (a) electrostatic bonds are stronger in ethanol than in water (b) van der Waals bonds do not form in ethanol (c) electrostatic bonds are weaker in ethanol than in water (d) Hydrogen bonds do not form in ethanol (e) a and d above 5. Which of the following explains why the side chains of hydrophobic residues are usually found in the interior of protein structures rather than on the outside of protein structures: (a) this minimizes the amount of hydrophobic surface area in contact with the aqueous solvent (b) the hydrophobic side chains can form more favorable hydrogen bonds with each other on...
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This note was uploaded on 12/09/2008 for the course BIOLCHEM 415 taught by Professor Michaeluhler during the Fall '06 term at University of Michigan.
- Fall '06