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Unformatted text preview: presence of the B-cell, this creates a response in the B-cell to make more of that antibody So many kinds of antibodies o Each B-cell can produce its own kind of antibody Only can have same # antibodies as # B-cells o How? Susumu Tonegawa o In the early 1970s, Tonegawa studied the creation of antibodies in B-cells o What he discovered earned him the Nobel prize for Physiology and Medicine in 1987 How Somatic Recombination works o Splicing of gene o Transcription of spliced gene o Translation of mRNA o Finished antibody...
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