lecture_10_06b

lecture_10_06b - Action Potential Module What you will...

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Recording electrode 1 (e1) Recording electrode 2 (e2) Stimulating electrode 1 Spike initiation zone (SIZ) Action Potential Module III.A.1. Experimentally simplifying the question. What you will learn in this module 1. You will learn that although passive electrical properties are important for neural integration, they are not adequate to carry neural information over long distances. 2. You will learn what an action potential is. 3. You will learn the mechanisms behind action potential generation. 4. You will learn about the importance of channels in neural signaling and that the conformation of channels can be changed by influences such as the voltage across the cell membrane, ionic concentrations, and time. 5. You will once again see the importance of the chemical and electrical forces in neural signaling as these forms of stored energy are released during the action potential. 6. You will learn that the stored energy released during action potentials will allow neural signals to travel far reaching distances with little attenuation.
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III . A.2 predicted results time (msec) Voltage at e1 (mv) time (msec) time (msec) 0 10 20 Voltage at e2 (mv) -60 -20 20 Stimulating electrode Weak Stimulation Moderate Stimulation Strong Stimulation Stim -60 -20 20 0 10 20 0 10 20 0 10 20 0 10 20 0 10 20 e2 e1 SIZ Predicted Recorded III.A.3. Actual results of experiments
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Let's focus on the middle panel from the previous figure and note important points. (1) The AP at electrode 2 starts at a slightly later time than the action potential recorded at e1.
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lecture_10_06b - Action Potential Module What you will...

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