Second Messenger System Review 2.ppt

Second Messenger System Review 2.ppt - Second Messenger...

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Second Messenger Systems Taziah Kenney, ATC
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Lipid Soluble Hormones Hydrophobic”/”Lipophilic” Diffuse directly into cell to nucleus Binds to receptor on chromatin Activates DNA transcription (mRNA) mRNA produces protein
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Action of Water Soluble Hormones “Lipophobic”/”Hydrophilic” hormones Cause effects on target cell through second messenger systems
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Water Soluble Hormone Mode of Action
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Second Messenger Systems Hormone binds to receptor cascade of metabolic events Best known system: Cyclic adenosine monophosphate (cAMP) Other system: Diacylglycerol & Inositol triphosphate (IP 3 )
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Hormones Activating
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