NPB 101, Autumn 2008.MIDTERM 1.
Outline of topics you need to focus on for WINGFIELD lectures for midterm 1.
Questions will come from powerpoints NPB.101.Lectures2.2008 to
NPB.101.Lectures7.2008. Questions on the midterm will be multiple choice (see the
example of a previous midterm exam on the course website). Note that of the 30
questions, 25 will come from the neurophysiology lectures given by Professor Wingfield
and 5 will come from Professor Weidner who will lecture next week.
Wingfield questions will focus on physiological function. You do not need to know the
DETAILS of anatomy, just the major points.
Membrane permeability, passive diffusion, facilitated diffusion, active transport.
Membrane potentials, ion channels, resting potential, graded potential, action potential.
Voltage gated channels, triggering events, parts of the neuron involved (input zone,
trigger zone, conducting zone, output zone). Refractory periods, contiguous and saltatory
conduction. Myelination. Synapses, synaptic transmission, postsynaptic responses.
Neurotransmission, neuromodulators, excitatory, inhibitory, temporal summation, spatial
summation, presynaptic inhibition and facilitation. Convergence and divergence.
Major subdivisions of the nervous system. Functional classes of neurons. Glial cell
functions. Ventricles of brain and cerebrospinal fluid functions. Brain meninges and their
Functional organization of the brain. Cerebrum and its lobes, basal nuclei. Gray matter,
white matter. Parietal lobe – major functions. Somatosensory cortex (sensory
homunculus). Frontal lobe – major functions, primary motor cortex and the motor