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Unformatted text preview: PHGY 209 I mmunology Lecture I I October 18, 2008 Humoral immunity End result of the immune response is generated by humoral or antibody molecules. (Will be cells involved in the generation) NK cells In innate immunity only, it is a major player in killing bacteria (because it can’t turn it off). Adaptive I mmune response Only does one more thing different from the innate immune response in an evolutionary point of view – it acquires a memory. Severe combined immunodeficiency (SCID) Born without an immune system and cannot generate an immune response. Bubble Boy No thymus. Lymph nodes are tiny. Bone marrow is abnormal. Until age of 3 to 4 months, we all have antibodies from our mothers, which were transferred through the placenta. AIDS 1982, cases of AIDS began. Now 60 million cases of H IV-AIDs-half are dead. Dead of infection because they have no immune defense. 90% of HIV infection exist in Africa. CD4+ helper T cells- the critical cell that is missing. Experiments of nature – you got to know what you got only because you know what happens when it is gone Vaccination...
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This note was uploaded on 12/25/2008 for the course PHGY PHGY 209 taught by Professor Annwechsler during the Spring '08 term at McGill.
- Spring '08