Infectious mononucleosisIs seen most commonly in adolescents and young adults. ( ages 15-40 )Mononucleosis is usually caused by the Epstein-Barr virus (EBV), which infects B cells (B-lymphocytes), producing a reactive lymphocytosis and atypical T cells (T-lymphocytes) known as Downey bodies.Mononucleosis is typically transmitted from asymptomatic individuals through blood or saliva ("the kissing disease"), or by sharing a drink, or sharing eating utensils.Symptoms usually appear 1-2 months after infection, and may resemble strep throat, or other bacterial or viral respiratory infections. The typical symptoms and signs :Fever- this varies from mild to severe, but is seen in nearly all cases. Tender and enlarged/swollen lymph nodes- particularly the posterior cervical lymph nodes, B/L Sore throat- White patches on the tonsils and back of the throat are often seen Fatigue(sometimes extreme fatigue) Some patients also display:Splenomegaly (which may lead to rupture) and/or Hepatomegaly (EBV hepatitis) Jaundice
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