Altered Cellular.docx - o o o o o o o o o o o o o o...

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Quiz: 15 min o Timed!!!Log in at 3pm and shut down at 3:15. Quiz: 1:30  min, 10 questions Multiple Choice Maybe T/F o Condense  page# with  Exams:  Paper Exams o Hand graded o Multiple choice, abcd 50 questions, 2 points each o Bonus points (iCollege with study material, AGB  interpretataion, dysrhythmia etc… will be explained week by  week) o No Final KNOW o Etiology o Characteristics o Definition o Know differentiation/types things…  o Compare/contrast two things NO PHARM questions Discussion Boards o 1 paragraph, read everyone's posts o Include "links"   Pathophysassignment o Design a broschure Handout is ok… Example will be on iCollege Pick a disease process that you are comfortable  with  Be Creative, no specific guidelines. Make it your  own To help your patients! Microsoft word has template Needs to have all the "sections" -grading guide Language: laymen's term Pathophysiology need to be easy and  condenses
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2 attachment dropbox; PDF brochure + PDF  Reference List ==>EMAIL Dr. Plitnick once what disease and who  the target audience   Cell Injury (look at all the ways cells can get injured) Compensatory mechanism overwhelming --> disease Cellular Adaptation
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  Atrophy - Decrease in cell size  (decrease in organ size) o   Physiologic - thymus (in early childhood) o   Pathologic - muscle atrophy after skeletal fracture (disuse atrophy  -->don't use it, loose it) How quickly does muscle atrophy? 24 hours! o   Disuse o Mechanisms: Decreased protein synthesis, increased protein  catabolism or both Hypertrophy – increase in cell size (enlarge) o Ex)Heart: cardiomyopathy, hypertrophy -->Left Ventricle ( sustain  High pressure to keep the aorta open -->the end result? Cardiac dysrhythmia  and cardiac arrest o Physiologic: Pregnancy, Working out Hyperplasia – increase in cell number o Happens with hypertrophy o Prolong  injury: ex) heart remodeling by division from injury, change function, --> it doesn't work corectly o Ex) Liver   Dysplasia – abnormal changes o Ex) Cervix/ Respiratory o Does NOT mean it's cancerous o It happens AROUND cancerous cells Metaplasia – mature cell replaced by another o Ex) Lungs (ciliated columnar cells--> mucous OUT)-->Smoking -->  ciliated cells replaced by squamous cells -->  functions change --> no cilia ->  can't get mucous out  o LOOSE THE PROTECTIVE MECHANISM  cell type   Cellular Injury
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    Cellular Injury o Cellular injury Reversible Irreversible  Ex) MI (Aconnetic) tissue   Biochemical Themes 1.  Adenosine triphosphate (ATP) depletion 2.  Oxygen & oxygen-derived free radicals 3. 
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  • Spring '14
  • DanaM.Meaney-Delman
  • Nursing

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