circulatory system notes.docx - Circulatory System Wednesday 5:31 PM Includes Blood Heart and Blood Vessels We are aerobic organism meaning we require

Circulatory System Wednesday, October 26, 2016 5:31 PM Includes Blood, Heart and Blood Vessels We are aerobic organism meaning we require oxygen in order for our body to function. Blood carries oxygen throughout our bodies. Circulatory system is a closed system, (pipes) Has one central pump to keep fluid circulating around. Two separate networks Pulmonary circuit: Blood goes through pulmonary circuit it goes through gas exchange. The release of CO2 in the blood and introduces new oxygen into the blood. Oxygenated blood comes to the heart it now needs to get pumped into the systemic circulation Systemic circulation: All blood vessels that go to our extremities, and brain. Everything but lungs, and send oxygenated blood to the tissues so cells can go through cellular metabolism. Fluid of the Circulatory System Blood : Connective tissue, made up of a fluid portion 55% liquid, solid cellular proportion formed elements the different types of cells. Most are red blood cells. They allow blood to be able to carry O2 and CO2. Without red blood cells you would have a limited capacity to carry gases. Total volume of blood 4-6L (average human 70kg) 2.6L plasma (liquid phase) 2.4 (cells of blood, formed elements). Hematology : Study of blood. Total body weight = 8% Liquid phase of blood(plasma)= 55% most is water, proteins, other solutes only small amount of gases can be dissolved Formed elements 45% 99% red blood cells (eurothrocytes) less than 1% platelets less than 1% leukocytes. Blood ph (measure of acidity or alkalinity)= Slightly alkaline PH 7.35 to 7.45 neutral is 7. Blood ph remains fairly stable throughout body. Unbalanced homeostasis: Acidosis Blood Donations Blood Plasma Mainly liquid will also have electrolytes and other nutrients. If you remove the clotting factors it is known as serum. Serum contains many antibodies. Formed elements of Blood

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Red make up 99% they provide hemoglobin which allows for oxygen carrying capacity and CO2. Leukocytes. Blood typing Blood is characterized by an ABO systems. Different antogens are present on the surface of red blood cells. Antogen is a protein. If it is found by immune cells it will think of it as foreign. Body will produce antibody to bind to the antogen and will trigger the rest of the body to attack that cell. Our blood can have an "A" antogen, "B" antogen, "an AB antogen, O no antogen. In the plasma the anti bodies for opposite letter If we are type A antogen we would have a B antibody If we are type B antogen we would have a A antibody If we are type AB antogen would not have any antibodies. Universal recipient If we are type O we do not have an antogen so you would have both anti A and anti B. Universal donar RH antogen (rhesis) You either have rh or you do not. You have a person RH positive can they do not to someone who is RH negative. It would stimulate an immune response and cause a production for RH response.