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Biochem notes document.docx - Introduction to Biochemistry...

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Introduction to Biochemistry Biochemistry the study of the chemistry of life o Concerned with Chemical/3D structure of biomolecules Synthesis/degradation of biomolecules Interaction of biomolecules Conservation and use of energy Organization/coordination of biomolecules Storage, transmission, and expression of genetic information Biomolecules Also referred to as macromolecules Contain C,N,O and H o Ca, P, K, S, Cl, Na and Mg are also found o Other trace elements are also present 4 types of biomolecules o Amino Acids o Carbohydrates o Lipids o Nucleotides Amino Acids Basic structure o Central α-carbon o α-amino group (NH 2 or NH 3 + ) o α-carboxyl group (COOH or COO - ) o R (reactive) group The R group determines what amino acid is present The α-amino group and α-carboxyl group are dependent on pH for ionization o α-amino: NH 3 + (pH0) NH 2 (pH14) Typically occurs at >7 o α-carboxyl: COOH (pH0) COO - (pH14) Typically occurs at <7
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