lecture 4-7 renal system III

lecture 4-7 renal system III - Chapter 44 (continued)...

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Chapter 44 (continued) – Hormonal control of kidney Learning objectives: • Distinguish between cortical and juxtamedullary nephrons. • Describe hormonal controls involved in the regulation of the kidney. • Describe what is involved in dialysis treatments.
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Figure 44.14 The nephron and collecting duct: regional functions of the transport epithelium Proximal tubule Filtrate H 2 O Salts (NaCl and others) HCO 3 H + Urea Glucose; amino acids Some drugs Key Active transport Passive transport CORTEX OUTER MEDULLA INNER MEDULLA Descending limb of loop of Henle Thick segment of ascending limb Thin segment of ascending limbs Collecting duct NaCl NaCl NaCl Distal tubule NaCl Nutrients Urea H 2 O NaCl H 2 O H 2 O HCO 3 - K + H + NH 3 HCO 3 - K + H + H 2 O 1 4 3 2 3 5
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Antidiuretic hormone ( ADH ). Situation: Physical activity on hot day results in profuse sweating…causing excessive loss of water… - ADH is released from hypothalmus when osmoreceptor cells in the hypothalmus detect a rise in blood osmolarity (> 300 mosm/L), - ADH reaches the kidneys by way of blood vessels…acts upon the distal tubules and collecting ducts by making them more premeable to water Result: Water is reabsorbed, re-enters the blood. * Also, ADH makes an individual seek water to quench thirst *
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Antidiuretic hormone (ADH) Increases water reabsorption in the distal tubules and collecting ducts of the kidney Figure 44.16a Osmoreceptors in hypothalamus Drinking reduces blood osmolarity to set point H 2 O reab- sorption helps prevent further osmolarity increase STIMULUS: The release of ADH is triggered when osmo- receptor cells in the hypothalamus detect an increase in the osmolarity of the blood Homeostasis: Blood osmolarity Hypothalamus ADH Pituitary gland
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This note was uploaded on 03/19/2008 for the course BIO 311D taught by Professor Reichler during the Spring '08 term at University of Texas at Austin.

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lecture 4-7 renal system III - Chapter 44 (continued)...

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