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Biol 216 8 Muscles 33-64.pdf

Biol 216 8 Muscles 33-64.pdf - Figure 50.28a-5 1 Thin...

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5/23/17 1 Figure 50.28a-5 Thin filament Myosin head (low- energy configuration) ATP Thick filament Myosin- binding sites Actin High-energy configuration ATP ADP P i ADP Cross-bridge Low-energy configuration Thin filament moves toward center of sarcomere. P i 3 4 2 1 5 P i ADP 4 3 5/23/17 33 Which band(s) will decrease when muscle shortens ? A. A Band and I band B. I Band and H zone C. A Band and H zone D. I Band only E. A Band only 5/23/17 34
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5/23/17 2 Which band(s) will decrease when muscle shortens ? A. A Band and I band B. I Band and H zone C. A Band and H zone D. I Band only E. A Band only 5/23/17 35 I A I H Sliding Filament Mechanism I A I 5/23/17 36
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5/23/17 3 Recall: I band is light,A band is dark 5/23/17 37 Sliding Filament Mechanism of Muscle Contraction Thin filaments slide over thick filaments simultaneously on each side of sarcomeres (note: the thick filament doesn’t slide) Shortens sarcomeres and muscle fibers Produces force that contracts the muscle 5/23/17 38
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5/23/17 4 a. Relaxed sarcomere Sarcomere Actin M line Myosin b. Contracted sarcomere H band 5/23/17 39 9-40 Relaxed Muscle Contracting Muscle 5/23/17
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5/23/17 5 How do you stimulate a skeletal muscle to contract? http://highered.mcgraw- hill.com/sites/0072495855/student_view0/chapter10/a nimation__action_potentials_and_muscle_contractio n.html 5/23/17 41 Muscle innervation Motor neurons : Stimulate muscle fibers to contract. Neuromuscular junction(NMJ): contact point between the axon and muscle 5/23/17 42
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5/23/17 6 Neuromuscular Junction Synapse : region where the axon terminal of a neuron rests on an invagination of the sarcolemma Neuromuscular junction: 1. Presynaptic terminal : axon terminal with synaptic vesicles 2. Synaptic cleft : space 3. Postsynaptic membrane (sarcolemma) or called: motor end-plate 9-43 5/23/17 Functionof NeuromuscularJunction Synaptic vesicles contain
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