Metabolism
Overview
Definition: sum of all cellular biochemical reactions
Types of Metabolic Reactions
Catabolism
o
Breakdown of complex molecules to simpler products (
Fig 13.13
) (Slide
1)
o
Produces energy (ATP) and reductants (NADH, FADH
2
, NADPH) and
heat
There is no such thing as a perfect machine
Energy and reductants consumed by anabolic reactions
Anabolism
o
Synthesis of complex macromolecules and cells from simpler precursors
(
Fig 15.2
) (Slide 2)
o
Also known as BIOSYNTHESIS
o
Requires reductants and energy input
There are only a few reversible metabolic reactions
o
Such pathways can function ana- and catabolically
Anabolical reactions- strong and Catabolical is weak
o
Known as AMPHIBOLIC PATHWAYS, e.g. some steps in Glycolysis
and the Krebs Cycle
Catabolic Reactions (e.g. Oxidation of Glucose)
Catabolite: substrate for catabolic reaction
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- Spring '08
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