Theme 5 Applied Lecture #2.docx

Theme 5 Applied Lecture #2.docx - Genome Wide Association...

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Genome Wide Association Study Identifying Linkage in a Pedigree The aim of linkage analysis is to identify a DNA marker found associated with the gene of interest so it can be used to track the gene within a family without actually knowing the mutation Wellcome Trust Case Control Consortium (WTCCC.; 2007) First large genome-wide association study to examine complex diseases using a SNP-chip or array Looking for linkage between a trait and millions of polymorphic SNPs
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