Drugs and the Brain Midterm 2 Review.docx - Midterm Review Exam Review today from 6-7 100 GPB Midterm Exam Two Next Tuesday Key Concepts Whiskey

Drugs and the Brain Midterm 2 Review.docx - Midterm Review...

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Midterm Review Exam Review today from 6-7 100 GPB Midterm Exam Two Next Tuesday Key Concepts: Whiskey tax (First drug legislation) proposed by Alexander Hamilton in 1700s rebellion in pennsylvania End of 19th century Department of Agriculture, then Department of Chemistry Schedule 1- No medical use accepted, marijuana, peyote, heroin Schedule 2- Cocaine, Opium Poppy Schedules 3,4,5- Less regulated Not scheduled- Alcohol, Caffeine, and Tobacco Marijuana Tax Act Harry J. Anslinger - 1930s pay tax if they wanted to sell marijuana as well as license - 1970s repealed and marijuana was scheduled Controlled substances Analogue act - Chemical analogues to scheduled drugs will be treated as if they are scheduled. Wording is pretty vague Cannabis Primary Psychoactive compound in cannabis is THC Primary reason it was discovered so late is it has no nitrogen in it Originally thought it was very hydrophobic and thus did mysterious things androgenous cannabinoid system discovered endocannabinoid system the receptors are in the presynapses Prevalence of Cannabis use in the US Chemical transformation of ethanol Alcohol dehydrogenase Tylenol has a very low therapeudic index Pharmacology of alcohol Alcohol reacts with GABBA agonist
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adenosene receptors Sedative hypnotics Barbiturates- phenobarbital, thiopental (used to be used for lethal injection but was only manufactured in one factorye Benzodiazepines- xanax, ativan, valium, klonipin (commonly prescribed for anxiety) (alzheimers study published that showed benzodiazepine correlation) Next generation of sed. hyp. - ambien, propofol, suvorexant, quaalude Anesthetics- Sedative Hypnotics - Original was diethyl ether (used as a solvent) - Chlorine is a common halogen, used to replace hydrogen and this is the family where most anesthetics come from. Inhalants- Hydrocarbons, volatile (evaporate easily), found in markers, glue - miscellaneous inhalants such as this include gasoline “Drugs and the Brain” Fall 2014 Key Concepts - 1 Some Key Concepts from “Drugs and the Brain” – Fall 2014 Useful as a guide for study; Not intended to be an exhaustive list Lecture 1 (8/28) • physicalism, world view • drug, droog, psychoactive drug • pharmaco, pharmakon • ethnobotany • power plants, plant teachers, ally • war on drugs, war on plants • drug war arrests • funding for prisons vs. finding for education Lecture 2 (9/2)
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