MI Fact Sheet.docx - MI Pathophysiology o Diagnosis o Coronary Atherosclerosis progressive chronic disease associated with endothelial dysfunction

MI Fact Sheet.docx - MI Pathophysiology o Diagnosis o...

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MI Pathophysiology : o Diagnosis: o Coronary Atherosclerosis: progressive, chronic disease associated with endothelial dysfunction, vascular inflammation, and accumulation of lipids and blood clotting elements within the lining of the coronary arteries o Transmural Infarction: involves the full thickness of the ventricular wall o Subendocardial Infarction: limited to the inner half of the myocardium o Signs/Symptoms: severe, prolonged chest pain or pressure; sweating, nausea, vomiting; increased levels of cardiac enzymes; ECG changes Management/Medications: o Goals: o To minimize the severity of clinical sequelae and slow/halt progression of disease o High risk patients: angioplasty or bypass surgery o Risk factor modifications: Smoking cessation Lipid modification Hypertension control Increasing physical activity Weight reduction Medications o Medications: Beta blockers
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ACE inhibitors Statins Aspirin Vitamin Supplementations and Food Source Modifications: 1. Vitamin E
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